Retatrutide and the Rise of Weight Loss Injections: What It Means for Your Skin
Retatrutide side effects and rapid weight loss can affect skin, face and muscle. Here’s how to support your skin alongside GLP-1 therapy.

Home > Notox vs Anti-Wrinkle Injections: What is the Real Difference?
Retatrutide side effects and rapid weight loss can affect skin, face and muscle. Here’s how to support your skin alongside GLP-1 therapy.
Is retatrutide available in Australia? Not yet. See the TGA status, Phase 3 trial results, safety warnings and what your real options are today.
Notox vs anti-wrinkle injections explained: one relaxes muscle, the other lifts skin. Compare onset, longevity and downtime.
Wondering how does SQT Bio-Microneedling works alongside other treatments? Our guide breaks down what you can stack for your skin concern.
Learn what to expect after SQT Bio-Microneedling and the proper aftercare routine, including how to use your recovery serum and what to avoid.
Standing at the mirror, tracing a frown line and wondering if it’s time for injections? It’s one of the most-searched aesthetic questions in Australia. The Notox vs anti-wrinkle injections choice comes down to two very different ways of treating the same concern. One relaxes the muscle that creases your skin. The other lifts, hydrates and rebuilds the skin and tissue itself. Plenty of clients use both, and that’s a great result too.
At Body Catalyst, we offer Notox, a non-invasive alternative many prefer.
Anti-wrinkle injections use botulinum toxin, which blocks the release of acetylcholine, the chemical messenger that tells a muscle to contract. A relaxed muscle can’t crease the skin above it, so frown lines, forehead lines and crow’s feet soften. The effect typically starts within 24 hours to two weeks of the injection.
It’s temporary, though. A review of the research found that most people lose maximum muscle effect after three to four months, so repeat appointments help maintain the look. In Australia, botulinum toxin is a prescription-only medicine, so an authorised practitioner needs to assess you first.
Injections do what they promise. They’re fast, precise and well studied. The trade-offs are the ongoing schedule, the cumulative cost, the risk of bruising, and a result that can feel restricting at high doses.
If you’re asking what Notox treatment is, it’s Body Catalyst’s needle-free, non-toxic approach to smoother, lifted skin. It’s a stack of five techniques working together:
Our Botox alternative comes as Signature Lift (HIFU and buccal massage), Signature Glow (NCTF, cryotherapy and lymphatic drainage) and Signature Transform (both). Quick 15–30-minute sessions target the neck, brows, or mouth.
A session feels more like a facial than a procedure, and with no downtime, you can head straight back to your day. Results are visible after your first session and continue to build as you work through your plan.

| Treatment | Notox | Anti-Wrinkle Injections |
|---|---|---|
| Mechanism | Stimulates collagen, lifts, hydrates and contours | Relaxes targeted muscles |
| Onset | Visible after the first session, building over a course | Days; full effect around two weeks |
| Longevity | Cumulative; plan set at consultation | Around three to four months |
| Expression | Natural movement stays | Can feel restricted |
| Downtime | None | Minimal; possible bruising |
| Needles | No | Yes |
Both treatments aim for the same result: smoother, fresher, younger-looking skin. They just take different routes. Injections relax the muscle that creases the skin. Notox lifts, hydrates and rebuilds the skin and tissue, so lines soften from the structure up.
Think about upkeep, too. Injections mean topping up a few times a year, and the cost adds up. Notox is built as a course, with your plan set at consultation, and results built over time.
Notox suits:
Anti-wrinkle injections suit:
Both can soften lines, but the results feel different. Injections smooth movement lines quickly and precisely. Notox softens lines gradually while lifting and hydrating the whole face, which suits a natural-looking finish. If a deep frown line is your only concern and you want it relaxed quickly, injections will usually take effect sooner.
Prefer to soften those same areas without injections? Body Catalyst has a few options. HIFU QuickLift sessions target the forehead, brow, and eye area, tightening the skin and stimulating collagen production. For a deeper side-by-side, read our HIFU vs Botox comparison. SQT Bio-Microneedling smooths fine lines and texture, and RF skin tightening firms the skin. If your skin looks slack or flat, non-surgical skin tightening can help.
These are often stacked, so your therapist can build a combination based on your lines and timeline.
Yes, and plenty of people do. Notox is needle-free and has no downtime, so it fits into whatever else is in your routine. If you’re with another clinic for anti-wrinkle injections, you can keep that appointment exactly as it is. Notox then adds what injections don’t: lift, hydration and collagen support in the skin around the treated areas.
Your injections keep working on movement lines, and Notox looks after the skin quality and structure underneath. Your therapist can help you plan sessions around your injection schedule so the two suit your calendar.
If you prefer to go completely non-invasive, we can also build a treatment plan to replace what injections do for you.
Body Catalyst is a needle-free clinic, so we have no reason to steer you towards or away from injections. Your free consultation is just the starting point to support your skin the way you need it.
Here’s how it runs:
Ready to talk it through? Book a free consultation at your nearest clinic.
Book a complimentary consultation with our Aesthetic & Wellness Therapists. During your complimentary consultation, your body expert will help answer any questions you may have about the technology and treatment process. From there, we will work with you to customise and recommend the best treatment program options to help you achieve your body goals.
Not sure which treatment is best for you? Call us today and speak with our Aesthetic & Wellness Therapists to discuss your body goals.